. Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1 , a Component of Bruch’s Membrane. It extends the capabilities of the original version, offering up to 60 percent increased gene detection sensitivity. PerkinElmer has launched the Sciclone G3 NGSx HT Workstation for automated next-generation sequencing library preparation. NIST characterized the material by size and using multiple reverse transcription droplet-digital PCR and qPCR methods. Link, D. C. (2018). It was validated in bladder, lung, liver, kidney, colon, breast, prostate, brain, thyroid, ovary, testes, and uterus tissue.The National Institute of Standards and Technology has developed a reference material to aid in the evaluation and development of RT-qPCR assays for SARS-CoV-2. non-contact liquid level detection technology ensures that all samples are processed using vacuum or pressure filtration. "This improvement reduces false positive and false negative results — including for common aneuploidies, expanded aneuploidies, microdeletions, and a baby’s sex," Myriad said in a statement, adding that the technology will also reduce the number of sampels that fail to produce a result due to low fetal fraction and deliver results to 99.9 percent of patients.Twist Bioscience is offering two new SARS-CoV-2 antibody panels for research use only.RareCyte has launched a new spatial biology analysis platform called Orion. It can automate cDNA synthesis from RNA or single cells as well as library construction from cDNA or gDNA. It can automate cDNA synthesis from RNA or single cells as well as library construction from cDNA or The Sciclone ® G3 NGSx HT workstation coupled with a new NEXTFLEX ® Rapid XP DNA-seq kit takes the guesswork out of the miniaturization in NGS library prep. The product can be used to characterize adaptive and innate immune cell diversity; identify and characterize rare cell types and biomarkers; analyze tissue microenvironment, disease progression, and drug immune response; perform large-scale antibody and TCR discovery for novel antigens; characterize immune responses to infection by measuring clonal expansions and immune cell phenotypes; and study genes and pathways with predesigned gene expression panels.This webinar, Part 1 of the “Advances in RNA-based Biomarker Development for Precision Oncology” webinar series sponsored by GeneCentric Therapeutics, will discuss how gene expression signatures can accelerate (and rehabilitate) drug programs, define targeted patient populations, expand drug indications, and improve clinical success.This webinar will discuss a study that combined single-cell gene expression and spatial gene expression to understand the evolution of sepsis in the kidney at the cellular and molecular level. PerkinElmer, Inc. 940 Winter Street Waltham, MA 02451 USA P: (800) 762-4000 or (+1) 203-925-4602 www.perkinelmer.com NGS Consumables Kit B (Part Number 6060009) A complete set of high quality consumables sufficient for a single single run of 96 samples through the 2-day Sciclone NGS/NGSx workflows, intended for the following reagent platforms: (2018) A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. Individual antibodies within the panel can be licensed for further therapeutic or diagnostic development.The Twist anti-SARS-CoV-2 S1 antibody panel include 32s human antibodies that bind with picomolar to nanomolar affinity to the S1 spike protein of the virus that causes COVID-19. PerkinElmer and 10x Genomics have created a complete automated workflow for long-read sequencing which maximizes high molecular weight gDNA extraction for a variety of sample types including saliva, DBS, blood, and plasma. Customize any validated method to your specific requirements or create methods from scratch for customer workflows.After the submission period and the final event in Hamburg, we are thrilled to announce the project selected to receive as a grant, the Sciclone® G3 NGSx iQ™ workstation…PerkinElmer has incorporated an on-deck thermal cycler (ODTC) to ensure full walk away automation for those who wish to have thermal cycling capability on deck. Diagenode, a firm providing epigenomics services and library prep products, has announced a new bulk 3' mRNA sequencing service, developed in collaboration with Alithea Genomics.All antibodies are cloned into human antibody backbones to generate VHH Fc, IgG1, or IgG2 antibodies. . Cell. The company is hoping that the technology will improve the performance of its Prequel NIPS test. Customers can also access the technology through RareCyte laboratory services and other specified programs.This webinar will address the utility of exome sequencing for neurodevelopmental disorders research and will provide details of a comparison study of two exome probe kits in this field of study.Myriad Genetics has launched Amplify, which sequences the fetal cell-free DNA fragments circulating in a mother's blood and increases the fetal fraction in a sample for non-invasive prenatal screening.