When effective levels of potassium bromide have been reached, if your dog’s seizures are well controlled, your veterinarian may be able to reduce or even eliminate the use of phenobarbital.
The amount of salt in the dog's diet affects how much potassium bromide is in the blood stream, so blood tests are often needed to establish the correct dose for a particular dog. The general dosage of Potassium Bromide is 20 to 40 mg per kilogram of body weight. Your dog will need regular blood tests to measure the concentrations of the antiepileptic drug. Epilepsy is sometimes the cause of seizures in both dogs and cats, No matter the cause, seizures can be frightening to witness. Symptoms of Bromide Toxicity in Dogs. Overall, the number of dogs with cluster seizures decreased (P = 0.0005).
Potassium bromide has a relatively long serum half-life (~24 days in dogs and 11 days in cats) and therefore requires a significant amount of time to reach a steady state (up to 4 months in dogs and 6 weeks in cats). Although potassium bromide is an effective drug, it can take as long as four months for the concentration of potassium bromide to reach effective levels. The maintenance dose is designed to maintain concentrations achieved after loading. Combination therapy was generally well tolerated and resulted in an improvement in seizure management in the majority of the dogs. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program.405 HERON DRIVE SUITE 200 • SWEDESBORO, NJ 08085-1749 | © 2004-2017 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED.This content is intended for counseling purposes only. At the beginning of treatment, your veterinarian may start your animal on a “loading dose” (higher than normal) in order to increase drug levels more rapidly. Overview of Bromides for Canines and Felines; A seizure is a convulsion or physical manifestation of abnormal brain electrical activity. This reaction may depend heavily on your pet’s diet.Dosage information for pet ownersPotassium bromide is a very common anticonvulsant medication used in dogs.
Potassium bromide is a compound that occurs naturally in your pet's blood. Both median MSF and MSDF decreased in the phenobarbital group (both P = 0.001) and in the KBr group (P = 0.004 and P = 0.003, respectively).
Other drugs that cause sedation may cause additional sedation when used with potassium bromide.Dr. Get it as soon as Tue, Aug 4.
The action appears to involve chloride ion channels which are an important part of the inhibitory neuronal network of the CNS. We conclude that phenobarbital or KBr add-on treatment decreases median MSF and MSDF in epileptic dogs refractory to a maximum dose of imepitoin.